April 12, 2026 · Introduction
Is It My Hormones?
Fatigue, weight gain, brain fog, low mood — hormones have become the default answer. This series covers what the evidence actually shows in three systems: thyroid, testosterone, and estrogen.
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Latest Series
Is It My Hormones? — Hormone Therapy Series
A 15-post series covering thyroid, testosterone, estrogen, and progesterone — what the evidence actually shows about hormone therapy, when it helps, when it doesn't, and what the wellness industry gets wrong.
Intro — Is It My Hormones?Read →
Set 1 · Post 1 — How the Thyroid Actually WorksRead →
Set 1 · Post 2 — Hypothyroidism: When Replacement Is IndicatedRead →
Set 1 · Post 3 — Hyperthyroidism and Thyroid NodulesRead →
Set 1 · Post 4 — Thyroid Myths and the Wellness IndustryRead →
Set 2 · Post 1 — What Testosterone Does (and Doesn't Do)Read →
Set 2 · Post 2 — Testosterone in Men: Indications, Protocols, MonitoringRead →
Set 2 · Post 3 — Testosterone in Women: HSDD and BeyondRead →
Set 2 · Post 4 — Gender-Affirming Care: Testosterone for Trans MenRead →
Set 2 · Post 5 — The Low-T Industry: What the Evidence ShowsRead →
Set 3 · Post 1 — The Menopause Transition: What's Actually HappeningRead →
Set 3 · Post 2 — Menopausal Hormone Therapy: The Evidence After WHIRead →
Set 3 · Post 3 — MHT: Risks, Benefits, and Who Shouldn't Take ItRead →
Set 3 · Post 4 — When You Don't Want or Can't Take HormonesRead →
Set 3 · Post 5 — Gender-Affirming Care: Estrogen for Trans WomenRead →
Topic Library
Series · Hormone Therapy
April 12, 2026 · Part 1 of 15
How the Thyroid Actually Works
The HPT axis, what TSH actually measures, why T4 isn't T3, and what "normal" thyroid function really means.
April 12, 2026 · Part 2 of 15
Hypothyroidism: When Replacement Is Indicated
Overt vs. subclinical hypothyroidism, T4 monotherapy vs. T4/T3 combinations, dose targets, and the monitoring schedule that actually makes sense.
April 12, 2026 · Part 3 of 15
Hyperthyroidism and Thyroid Nodules
Graves' disease, toxic nodules, thyroiditis — causes, symptoms, treatment options, and when thyroid nodules require biopsy versus watchful waiting.
April 12, 2026 · Part 4 of 15
Thyroid Myths and the Wellness Industry
Adrenal fatigue, reverse T3, Wilson's syndrome, and why the TSH range isn't a conspiracy — what functional medicine thyroid claims actually look like under scrutiny.
April 12, 2026 · Part 5 of 15
What Testosterone Does (and Doesn't Do)
How testosterone is made, what it regulates, what normal ranges mean, and why the energy-libido-vitality narrative is more complicated than the wellness industry admits.
April 12, 2026 · Part 6 of 15
Testosterone in Men: Indications, Protocols, and Monitoring
When testosterone replacement is actually indicated, which formulations work best, what labs to check and when, and how to have honest conversations about fertility.
April 12, 2026 · Part 7 of 15
Testosterone in Women: HSDD and Beyond
The one FDA-recognized indication for testosterone in women, what the evidence shows for energy and mood, safe dosing ranges, and why supraphysiologic doses carry real risk.
April 12, 2026 · Part 8 of 15
Gender-Affirming Care: Testosterone for Trans Men
Informed consent vs. gatekeeper models, what physical changes to expect and when, fertility considerations, and the monitoring schedule for masculinizing hormone therapy.
April 12, 2026 · Part 9 of 15
The Low-T Industry: What the Evidence Shows
How testosterone marketing turned a medical condition into a lifestyle brand, what clinical trials actually show about testosterone for age-related decline, and what to watch for in a Low-T clinic.
April 12, 2026 · Part 10 of 15
The Menopause Transition: What's Actually Happening
Perimenopause to postmenopause — the biology of the transition, how long symptoms actually last, which symptoms are directly caused by estrogen loss, and how to set realistic expectations.
April 12, 2026 · Part 11 of 15
Menopausal Hormone Therapy: The Evidence After WHI
What the Women's Health Initiative actually found, why it was misinterpreted for two decades, and what the evidence now shows about who benefits from MHT and when to start.
April 12, 2026 · Part 12 of 15
MHT: Risks, Benefits, and Who Shouldn't Take It
Absolute risk numbers for breast cancer, VTE, and stroke — not relative risks — plus who should take estrogen alone, extended use considerations, and clear contraindications.
April 12, 2026 · Part 13 of 15
When You Don't Want or Can't Take Hormones
Non-hormonal options for vasomotor symptoms — what actually works, what doesn't, and why vaginal estrogen belongs in a completely different conversation from systemic MHT.
April 12, 2026 · Part 14 of 15
Gender-Affirming Care: Estrogen for Trans Women
Informed consent model, physical changes and timeline, what's reversible and what isn't, fertility considerations, VTE risk, and the monitoring schedule for feminizing hormone therapy.
Series · GLP-1 Medications
April 6, 2026 · Part 1 of 7
What Are GLP-1 Medications?
How semaglutide and tirzepatide work, what makes them different from previous weight-loss drugs, and what FDA approval actually means.
April 6, 2026 · Part 2 of 7
Long-Term Safety and Side Effects
What the long-term trial data actually shows about GI side effects, thyroid concerns, pancreatitis risk, and who should not take these medications.
April 6, 2026 · Part 3 of 7
How Much Weight Will You Actually Lose?
Real-world weight loss averages from clinical trials, how results vary by individual, and what "up to 22%" actually means in practice.
April 6, 2026 · Part 4 of 7
Keeping the Weight Off
Why weight returns after stopping GLP-1 medications, what the STEP trial extension showed, and how to build a long-term maintenance plan.
April 6, 2026 · Part 5 of 7
The Combination That Beats Either Alone
How exercise and protein intake amplify GLP-1 results, protect muscle mass, and change what happens when you eventually taper the medication.
April 6, 2026 · Part 6 of 7
Compounding, Counterfeits, and Common Myths
What compounded semaglutide actually is, the FDA's position on it, counterfeit risks, and the most common misconceptions about GLP-1 medications.
April 6, 2026 · Part 7 of 7
GLP-1 Medications and Fertility
What the evidence shows about GLP-1 medications, PCOS, menstrual cycles, contraception interactions, and pregnancy — with clear guidance on when to stop.
Series · The Common Cold
April 1, 2026 · Part 1 of 5
What Is the Common Cold?
What's actually happening in your body during a cold, what to expect, and why it almost always gets better on its own.
April 1, 2026 · Part 2 of 5
When a Cold Is More Than a Cold
How a common cold can become dangerous for people with asthma, COPD, weakened immune systems, or heart disease — and which vaccinations help.
April 1, 2026 · Part 3 of 5
What Actually Works at the Pharmacy
A frank look at cold medications: what's backed by evidence, what to skip, and why the good decongestant is behind the counter.
April 1, 2026 · Part 4 of 5
The Underrated Cold Remedy
Nasal saline irrigation — the one home cold remedy with real evidence behind it. How it works, isotonic vs. hypertonic, and how to do it correctly.
April 1, 2026 · Part 5 of 5
When to Call Your Doctor
How to tell when a cold is turning into a bacterial complication — warning signs, when to call the clinic, and when to go to the ER.
April 1, 2026 · Primary Care
Understanding membership-based primary care
What membership-based primary care actually means, how it differs from a traditional practice, and whether it's a good fit for you.
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